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RESOURCES

NEUROBIOLOGY LAB: Interoceptive Nutrient Sensing in Flies and Mice 

※ RESOURCES board is available only in the Web version.

DH44 neurons, 20mM glucose

They are activated by caloric D-glucose.

Dus, Monica, et al. "Nutrient sensor in the brain directs the action of the brain-gut axis in Drosophila." Neuron 87.1 (2015): 139-151.

Ex vivo Calcium imaging of pancreas

Ex vivo Calcium imaging of pancreas by using fluo-4AM.

Recording by Seong Ju Lee

Fiber photometry: PVN-CRF_ GCaMP6 I

They are inhibited by peanut butter consumption in fed state.

Kim, Jineun, et al. "Rapid, biphasic CRF neuronal responses encode positive and negative valence." Nature neuroscience 22.4 (2019): 576-585.

Fiber photometry: PVN-CRF_ GCaMP6 II

They are activated rapidly by visual looming cue.

Kim, Jineun, et al. "Rapid, biphasic CRF neuronal responses encode positive and negative valence." Nature neuroscience 22.4 (2019): 576-585.

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